Regulation of GPR54 Signaling by GRK2 and β-Arrestin
نویسندگان
چکیده
منابع مشابه
Regulation of Constitutive GPR3 Signaling and Surface Localization by GRK2 and β-arrestin-2 Overexpression in HEK293 Cells
G protein-coupled receptor 3 (GPR3) is a constitutively active receptor that maintains high 3'-5'-cyclic adenosine monophosphate (cAMP) levels required for meiotic arrest in oocytes and CNS function. Ligand-activated G protein-coupled receptors (GPCRs) signal at the cell surface and are silenced by phosphorylation and β-arrestin recruitment upon endocytosis. Some GPCRs can also signal from endo...
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ژورنال
عنوان ژورنال: Molecular Endocrinology
سال: 2009
ISSN: 0888-8809,1944-9917
DOI: 10.1210/me.2009-0013